p-ERK1/2 (Thr202/Tyr204)
分类: 最上层  发布时间: 2018-03-20 19:02 

p-ERK1/2 (Thr202/Tyr204)
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货号: WLp1512
抗体名: p-ERK1/2 (Thr202/Tyr204) 抗体
抗体英文名: p-ERK1/2 (Thr202/Tyr204) Antibody
浓度: >1mg/ml
应用范围: WB,IHC
宿主:
适应物种: H,M,R
标记物:
克隆性:
保存条件: -20℃
形态: 液体
亚型: IgG
规格: 50μl(>50μg)
本公司所有一抗,50μl(>50μg)现价450元/支,全部现货,均提供20μl免费试用装,详情请点击免费试用
 
产品货号 WLP1512
产品名称 p-ERK1/2 (Thr202/Tyr204) Antibody
预测分子量 42/44kDa
别名 P-ERK1;P- ERK2;P- ERT1;P- ERT2; P-MAPK1;  P-MAPK2;  P-MAPK3; P- P42mapk;  P-P44erk1; P-PRKM1;  P-PRKM2;  P-PRKM3
浓度 >1 mg/ml
免疫原 合成p-ERK1/2 (Thr202+Tyr204) 多肽
抗体来源
特异性 抗人,小鼠,大鼠
克隆类型 多克隆抗体
产品应用 WB;IHC
成分 亲和纯化抗体,20 mM PBS,150 mM NaCl,100 μg/ml BSA,50%甘油,NaN3<0.02%
保存条件 -20℃保存
背景资料 Extracellular signal-regulated kinases Erk1 (p44 MAPK) and Erk2 (p42 MAPK) Serine/Threonine protein kinase are part of a subfamily of mitogen-activated protein kinases. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors and cytokines. Upon stimulation, a sequential three-part protein kinase cascade is initiated consisting of a MAP kinase kinase kinase (MAPKKK or MAP3K), a MAP kinase kinase (MAPKK or MAP2K) and a MAP kinase (MAPK). Phospho-ERK1/2 is negatively regulated by a family of dual-specificity (Thr/Tyr) MAPK phosphatases, known as DUSPs or MKPs (10), along with MEK inhibitors such as U0126 and PD98059.
 
 
 
 
 
 
 
 

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